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Viagra (sildenafil) facts
What is Viagra?
Viagra is the trade name for a drug called Sildenafil. Viagra is one of a class of drugs known as PDE-5 (Phosphodiesterase type 5) inhibitors.
Viagra and the other PDE-5 inhibitors can help men with erectile dysfunction (male impotence) by enhancing the erectile response when a man is sexually stimulated. Aside from Viagra, the other drugs in this class are Cialis (Tadalafil) and Levitra (Vardenafil).
How does Viagra work?
Viagra does not cause a man to be sexually aroused. Viagra is only effective if you are sexually aroused. To understand how it works you need to understand the mechanics of how a man gets an erection. When you get sexually stimulated, the nervous system in the erectile tissue of your penis releases nitric oxide (NO).
The nitric oxide stimulates an enzyme that produces something called a messenger cyclic guanosine monophosphate (cGMP). The cGMP relaxes the smooth muscle cells. One result of this is that the arteries in your penis dilate and the blood can flow into your penis more easily. Another result is that the erectile tissue itself fills with blood. Both of these process result in an erection. Viagra works by maintaining the level of cGMP in the smooth muscle cells.
If you are not turned on, your brain will not stimulate the release of any nitric oxide and you will not produce any cGMP.
Is Viagra effective?
Clinical studies have shown that when compared to placebo, Viagra and the other drugs in the same class, result in significant improvement in erectile function. Although established to be a safe and effective drug, Viagra isn’t appropriate for everyone and may not work in all cases.
How does it affect blood pressure?
Viagra can slightly lower blood pressure. This is not a problem for most men. But Viagra’s effect on blood pressure is exaggerated if the Viagra is taken with a nitrate drug.
Nitrates are one of the treatments doctors prescribe for angina. If you take Viagra when you are also taking nitrates, the combined effect of the Viagra and the nitrates can lower your blood pressure to such an extent that it could prove fatal. Never take Viagra at the same time as taking nitrates.
If I have a heart condition can I take it?
If you have a heart condition it is important that you discuss this with the doctor before taking Viagra. Viagra may not be appropriate because of the danger of interacting with the nitrates.
Can women take it?
Viagra is not currently licensed for use by women.
How quickly does it work?
On average, Viagra becomes effective in just under an hour when you take a tablet on an empty stomach. Viagra can remain effective for between four and six hours. If you take it after a meal that has a high fat content, it may take longer than an hour to become effective.
Why are there different doses?
Viagra is available in three dosages: 25mg, 50mg and 100mg. Some men may respond to a lower dose of Viagra. Some men may already be taking medicines that interact with Viagra and thus need to adjust the Viagra dosage they are taking.
What dose is right for me?
The doctor needs to decide which dosage of Viagra is most appropriate. The doctor will take into account potential drug interactions, your age, the severity of your erectile dysfunction and any previous experience you have had with Viagra.
What if it does not work the first time I use it?
Viagra might not work the first time you take it. Most doctors advise taking Viagra at least eight times before trying a different medicine.
What are the side-effects?
Viagra’s Side effects are generally mild and brief. Viagra’s most common side-effects are headache and facial flushing. Less frequently, men taking Viagra have reported indigestion, a stuffy nose and a blue tint to the vision.
Does it interact with other medicines?
Viagra interacts with many drugs. The following list is not complete but it is important to inform the doctor of all prescription and non-prescription medication taken, especially:
- nitrate medications (e.g. glyceryl trinitrate (GTN), nitroglycerin, isosorbide mononitrate or dinitrate)
- azole antifungals (e.g. itraconazole, ketoconazole)
- rifamycins (e.g. rifampicin)
- Alpha blockers, prescribed for prostate disease or high blood pressure
- Ritonavir, Amyl, Butyl or Isopropyl nitrates (‘Poppers’)
Who shouldn’t use it?
Men who have any of the following conditions should also avoid taking it:
- severe heart or liver problems
- recent stroke or heart attack
- low blood pressure
- certain rare inherited eye diseases
Does it treat the underlying causes of impotence?
Viagra will resolve the underlying cause of erectile dysfunction although if the cause is primarily psychological, it may help to break the cycle of anxiety and failure associated with being unable to achieve a satisfactory erection.
What kind of tests might highlight the underlying causes of male impotence?
A blood test for diabetes should be performed along with cholesterol and triglyceride blood tests. It is becoming increasingly accepted among doctors that sex hormone levels (Testosterone) should also be checked by way of a blood test.
What other impotence treatments are available?
The other drugs, Levitra and Cialis work in similar ways. Viagra is generally prescribed as the first line treatment. Cialis has a much longer half-life than Viagra and Levitra and therefore its effect lasts much longer.
This does not mean one has prolonged erections but the length of time available for further erections is increased without the need to take further doses. It also means however that the side effects if present will last longer. Levitra, like Cialis, can be taken with food whereas Viagra should be taken on an empty stomach.
Some studies have shown Levitra to be more suitable for men suffering from diabetes. Other treatments include Caverject (‘Alprostadil’), which is a medication injected directly into the penis and MUSE (another form of ‘Alprostadil’), which is a pellet inserted into the urethra. These may be of use for men who have to take Nitrates and are therefore unable to take the PDE5 inhibitors.
The use of vacuum pumps and other mechanical devices for producing and maintaining erections are alternatives to taking medication.
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What To Expect First Time Using Viagra
What To Expect First Time Using Viagra in Snow Hill, Maryland is small town living at its best. Nestled on the south banks of the Pocomoke River Snow Hill is a place where people know each other. From the people who call it home to the business owners and those in city government, we have built a community where life is gentle, fun, and prosperous. Home to a quaint downtown retail area and a broad spectrum of recreational activities, What To Expect First Time Using Viagra is the perfect place to spend a relaxing weekend or a lifetime.
Whether you are interested in researching your genealogy in the Worcester Room of the Worcester County Library. renting a kayak from the Pocomoke River Canoe Company to paddle on an undeveloped natural river, or studying the architecture of historic homes and beautiful churches while taking the Historic Walking Tour, What To Expect First Time Using Viagra has something for everyone. You will find recreational opportunities in Byrd Park and Sturgis Park, artifacts at the Julia A. Purnell Museum. and treasures in the shops and art galleries.
The beautiful rural setting boasts rich farmland that has been the mainstay of the economy of the county seat of Worcester County for centuries. The rich heritage of this area is celebrated daily at Furnace Town Living Heritage Museum and during a summer festival every August with The Blessing of the Combines.
The town of What To Expect First Time Using Viagra welcomes you as you explore our small town steeped in history and tradition but alive with charm and activities.
Comment from: Jason9, 35-44 Female on Treatment for 1-2 years (Patient) Published: October 07
Very effective. Take without food to help absorption quickly and last longer. Effect does *not* run out in 4 hours. I have taken as little as 10-15 mg and felt the benefits for well over 12 hours. This of course will be different for everyone. Would recommend starting with a very, very low dose. My first dose of 25mg made my penis hurt due to the long lasting and persistent erections. Here are my recommendations and items to consider based on my personal experience: 1. Take without food 1 hour before love-time. It takes a bit to kick in. I have always felt a little “preview” effect of Viagra in about 15 minutes. but then it really kicks in after an hour. To get the Viagra flowing through your penis, manipulate yourself a little (may not take much. just an extra few giggles in the restroom). 2. Drink lots of water. Dehydration is BAD for erections. 3. Pop a couple of tums or rolaids. Viagra can make your stomach acidic. 4. Pop a breath mint as it can give you tart breath. 5. Take a very, very low dose the first time. Also, take it while you are alone so you can get used to how much you really need and the benefits. DON’T take it for the first time with your partner. 6. Don’t take it too often because it can make your prostate swell up. So don’t take it every other day so you can masturbate for 3 hours. 7. Headaches are common. pop a couple Advil with it. 8. Once you are having sex, it will keep your erection going even if what you are doing doesn’t feel that good. This is BAD. You don’t want to get used to having sex in positions that don’t feel good to you, since your erection will continue, but you may not be able to “get back into it” and have an orgasm. Certainly, there are times when this may be okay, but it gets awkward when you are in bed with a woman, have a rock hard erection, and you can’t have an orgasm. Women ask questions. And if she doesn’t know you are taking Viagra, she will probably figure it out. Good luck.
Comment from: New_user, 45-54 Female on Treatment for less than 1 month (Patient) Published: October 20
This drug worked extremely well for me. My doctor recommended that I start with 100 mg which I did with results that would put a teenager to shame. I experienced a mild headache the next morning and some nasal stuffiness. I also experience a very slight sensitivity to light. (These are all documented side effects and not considered unusual). I cut the dosage to 50 mg and the side effects virtually disappeared. without any noticable decrease of the drug’s effectiveness. I even tried 25 mg with good results. With 100 and 50 mg dosing, the effect of the drug kicked in after only 15-20 minutes. And the results lasted much longer than the advertised 4 hours – as much as 12 -14 hours for me. With this drug, I’ve been able to ejaculate every time and the erection does go away as promised (something I was concerned about after hearing the warning of the “4 hour erection” in the commercials). This drug has given me back my lovelife and in a way that has made it better than it’s ever been. If you’re having issues, but not sure what to do, I strongly encourage you to visit with your doctor and see if this drug (or similar) will work for you. I guarantee that, if it does (and my doctor tells me it is almost always effective), you will be the happiest guy on your block! Good luck!!
Comment from: working at it, 45-54 Female on Treatment for 2-5 years (Patient) Published: February 11
Guys, listen up.This is not a cure all. You have to experiment to see what works for you. First, you are paying by the pill and it’s crazy exspensive. Buy a pill splitter and cut your price in half or by 75% depending on the dossage you need. It takes practice to get a perfect cut but i’ts worth the effort. If you drink alcohol you’ll have to see how much you can consume with out diminishing results which is about 6 beers for me. Also I have found that I can take it at 10 or 11 at night and wake up with a raging hard on the next day which works out perfectly in my relationship and lasts till late afternoon. By the way I’m 50 and had a heart attack when I was 42.
Comment from: 35-44 Female on Treatment for less than 1 month (Patient) Published: December 24
Works great. I am only 40. Started having problems about a year ago. Got a sample pack from Dr. with 6 pills. The first three I took worked perfectly. Took on empty stomach or at least one hour after a meal. Within an hour, took effect. Makes my face flush and nose run (common side effects) The fourth time I took it, I split the pill in half to see if it would work at lower dose (I was taking a 50mg dose) This DID NOT work. I dont know if it was the lower dose, if it had something to do with what I ate beforehand (Mexican food), or if your not supposed to split them. Also, most of the time, it still has effects several hours after. Even up to the next morning if taken at night.
Comment from: CallhimMrHappy, 45-54 Female on Treatment for less than 1 month (Patient) Published: August 26
Am 46 years old and just started having problems getting erections. Tried “herbal” remedies, was hit or miss, mostly miss. Also libido was on the down turn, I just didn’t feel like I needed or wanted sex. Talked to Dr and was given free trial of 50 mg. Took one a hour before bed, and was very amazed at the erection it gave me when the wife and I started messing around! Not to mention waking up with morning wood, something that hasn’t happened in a LONG time!
Patient Comments are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified health provider because of something you have read on RxList. The opinions expressed in the comments section are of the author and the author alone. RxList does not endorse any specific product, service or treatment.
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