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Il citrato di sildenafil, il cui nome commerciale più diffuso è Viagra. è un farmaco sviluppato. La concentrazione ematica del farmaco, in effetti, raggiunge i valori massimi entro. Le verità scientifiche sul Cialis a proposito delle controindicazioni ed effetticollaterali. Poiché alcune medicine interessano anche il metabolismo delCialis. Quali sono gli effetti collaterali di Cialis. si verifica qualcuno dei seguenti effetti indesiderati interrompa l'uso del medicinale. 13 feb 2007 . In Italia è sempre più diffuso l'utilizzo del Viagra. Ma è vero. E quali gli effetticollaterali. È vero che chi prende il Viagra rischia un infarto?11 nov 2012 . Conoscere le controindicazioni del Cialis e i suoi effetti collaterali è importante perché il farmaco, utilizzato per trattare i sintomi della. L'azione del Cialis è quella di distendere i muscoli nel pene ed i vasi sanguigni, un'azione prolungata (fino a 36 ore) e con il minimo di effetti collaterali .22 feb 2016 . Le controindicazioni e gli effetti collaterali a livello organico di questi tre. L' assunzione di questi farmaci (ad eccezione del Cialis e dei farmaci. 24 feb 2014 . Hanno fattori di rischio ed effetti collaterali in parte sovrapponibili. Il Citrato di Sildenafil, il principio attivo del Viagra. può aiutare a liberare. Il dosaggio del Cialis dipende molto dalla problematica e rettili di ogni singola rischi nell'assumerne troppo e gli effetti collaterali che ne sono correlati. Il Cialis. Disfunzione erettile e sildenafil (Viagra ). Riproduzione parziale di un documento del Ministero della Sanità (1998). Parte 4 di 8. Bibliografia. .

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Beckenbodentraining gegen Impotenz

Die Erektion des männlichen Gliedes ist ein komplexer Prozess, bei dem mehrere Faktoren zusammenpassen müssen. Neben seelischen Faktoren, wie z. B. Stress oder Überlastung, kommen organische Gründe hinzu. Da ist z. B. Übergewicht oder mangelnde sportliche Ausdauer zu nennen. Eine einzige Ursache kann schon eine ausreichende Schwellung verhindern. Ist der Mann ansonsten gesund, ist eine gut trainierte Beckenbodenmuskulatur eine wichtige Randbedingung für eine kraftvolle Erektion.

Wenn der Beckenboden eines Mannes erschlafft ist, kann es nicht zu einer dauerhaften, ausreichenden Anschwellung des Gliedes kommen. Die Venen, aus denen das Blut aus den Schwellkörpern abfließt, werden normalerweise durch die Muskulatur des Beckenbodens abgepresst. Ist dies nicht mehr der Fall, kann das in die Schwellkörper einströmende Blut keine ausreichende Erektion auslösen. Egal wie hoch die Erregung auch sein mag, das Blut fließt ungehindert aus den Schwellkörpern heraus und die nötige Versteifung tritt nicht ein.

Inhalt dieser Seite

Was versteht man unter dem Beckenboden?

Unter dem Beckenboden versteht man das untere Bindegewebe, das die Organe der Beckenhöhle zum After hin abgrenzt. Es werden drei Teile unterschieden. Der Erste ist der »Diaphragma Pelvis«. Dies ist der hintere Beckenbodenteil, der vom Mastdarm durchbrochen wird. Der Zweite ist der »Diaphragma urogenitale«, das ist der vordere Beckenbodenteil. Als Drittes ist dann noch die Schwellkörper- und Schließmuskelschicht. Diese Schicht besteht aus drei Muskeln mit den Bezeichnungen »Musculus ischiocavernosus«, »Musculus bulbospongiosus« und »Musculus sphincter ani externus«. Von diesen Muskeln sind die beiden Erstgenannten die für die Erektion und dem Geschlechtsverkehr bedeutsamen. Der letzte Muskel ist, man ahnt es schon, der Schließmuskel des Mastdarmes.

Der В»Musculus ischiocavernosusВ«

Der Name dieses, für die Erektion besonders wichtigen Muskels, kann man kaum ins Deutsche übersetzen. Er bezeichnet die Lage, in der dieser Muskel am Beckenboden verläuft und könnte mit »Muskel, der vom Gesäß zu Schwellkörper verläuft« beschrieben werden. In der Tat läuft dieser Muskel parallel zu den inneren Schwellkörpern des Penisschaftes und ist maßgeblich für die Drosselung des zurücklaufenden Blutes verantwortlich. Wenn dieser Muskel ohne Spannkraft ist, bleibt jeder Versuch eine Erektion aufzubauen ohne Erfolg. Doch vorab die gute Nachricht: Der Muskel kann sowohl reflektorisch als auch willkürlich angespannt werden, davon später mehr.

Der В»Musculus bulbospongiosusВ«

Unterstützend zum »Musculus ischiocavernosus« umschließt dieser Muskel den Penisschaft. Er dient zum völligen Entleeren der Harnröhre und zur Unterstützung der Ejakulation. Zusätzlich begünstigt er den Blutfluss in die Penisschwellkörper (corpus cavernosum). Auch dieser Muskel kann willkürlich und reflektorisch angespannt werden.

Was ist Beckenbodengymnastik?

Unter dem Begriff Beckenbodengymnastik, Beckenbodentraining oder auch nach seinem Erfinder, Arnold H. Kegel (1894–1981), Kegelübung genannt, versteht man die Festigung des Beckenbodens durch geeignete Gymnastik. Das Training ist für viele Menschen schwierig, weil die Muskeln verborgen sind und nicht zu den Muskeln zählen, die normalerweise bewusst beansprucht werden.

Der erste Schritt zu einem erfolgreichen Beckenbodentraining ist die Konzentration auf diesen. Durch gezielte Anspannung werden dann die einzelnen Muskeln bzw. Muskelgruppen trainiert. Es wird empfohlen, die Übung zunächst mit einer geschulten Person zusammen durchzuführen. Kombiniert mit der Stärkung des Beckenbodens wird gerne auch das gesamte Becken und die Rückenmuskulatur mit in die Übungen einbezogen.

Geeignet ist das Training für jedermann, der nicht durch eine frische Operation oder Entbindung belastet ist. Wird das Training regelmäßig und korrekt durchgeführt, stärkt es die Beckenbodenmuskulatur und dient so der Vorbeugung zahlreicher Krankheiten. Neben der Erektionsstörung wird Harninkontinenz bei Prostataleiden gelindert bzw. geheilt. Zusätzlich wird die vorzeitige Ejakulation beim Geschlechtsverkehr erfolgreich kuriert.

Für den Mann, der Hilfe bei Erektionsstörungen sucht, hat das Beckenbodentraining zahlreiche weitere Vorteile. Die Nebenwirkungen der Medikamente entfallen komplett. Hitzewallungen und Dauererektionen, wovon nach der Einnahme gängiger Medikamente zur Erektionsverbesserung immer wieder berichtet wird, sind bei der Anwendung einer durchdachten Gymnastik noch nie vorgekommen. Zudem hat Beckenbodentraining etliche angenehme Begleiterscheinungen. Durch die verbesserte Muskelspannung ist die Körperhaltung aufrechter und der Gang wird fließender. Dies hat wiederum eine direkte wohltuende Wirkung auf die Psyche. Menschen mit trainiertem Beckenboden sind vitaler und kontaktfreudiger.

DarГјber hinaus wird das Liebesleben bereichert. Der Akt endet wieder mit einem Samenerguss und nicht mit dem Abbruch aus mangelnder Kondition.

Wie gut hilft Beckenbodengymnastik?

Selbst bei einer diagnostizierter veno-okklusive Dysfunktion (venöses Leck) möchten nicht alle Männer Medikamente einnehmen. Zahlreiche Studien belegten, dass die Hauptursache einer Erektionsstörung, selbst bei ausreichendem arteriellen Blutstrom, der ungehinderte Abfluss des Blutes ist. So wirken alle bekannten Medikamente in erster Linie dahin gehend, diesen Rückfluss zu minimieren. Zur großen Verwunderung stellten Ärzte fest, dass nach nur wenigen Stunden Beckenbodengymnastik die Erektionsfähigkeit der Probanden ähnlich stark zunahm, wie nach der Einnahme gängiger Medikamente.

Genau besehen ist dies wenig verwunderlich. Die Medikamente zielen darauf ab, genau diese Muskeln zu beeinflussen. Was Physiotherapeuten mit Training erreichen, das wird von den Medikamenten chemisch über Enzyme gesteuert. Das Ergebnis ist praktisch gleich. Bei einer sexuellen Erregung kommt es zu der gewünschten Erektion, die durch Beckenbodengymnastik genau so ausgeprägt ist wie die durch gängige Medikamente.

Wie trainiere ich meinen Beckenboden?

Um einen wirklichen Erfolg zu haben, muss der Beckenboden regelmäßig, am Besten sogar täglich, trainiert werden. Geräte braucht man als Mann für das Training keine. Weil die Übungen im Wesentlichen auf das Anspannen bestimmter Muskeln im Unterbauchraum basieren, kann man das Training sogar heimlich im Büro durchführen.

Im Folgenden eine Anleitung für das Erlernen der Beckenbodengymnastik. Falls sich der gewünschte Erfolg nicht einstellen sollte, suchen Sie bitte eine Fachkraft auf! Obwohl man im Prinzip nichts falsch machen kann, ist es dennoch gut möglich, dass wesentliche Prinzipien der Gymnastik falsch umgesetzt werden. Das Training zeigt dann nicht den gewünschten Erfolg und es wurde u. U. viel Zeit vergeudet. Bei der folgenden, möglichst einfach gehaltenen Anleitung, wurde großen Wert auf eine gute Umsetzbarkeit und einen nachhaltigen Erfolg gelegt.

EinfГјhrung in das Training

Um einen wirklichen Erfolg zu erzielen, sollte am Anfang die richtige Atmung im Mittelpunkt stehen. Legen Sie sich dazu in einer ruhigen Umgebung auf den Rücken. Ziehen Sie die Füße zu Ihrem Gesäß und grätschen sie die Beine leicht. Nehmen Sie einen Hocker oder eine Decke zur Hilfe. Die Haltung sollte möglichst bequem sein und die Bauchdecke entlasten. Ihre Hände legen Sie locker auf den Bauch, damit sie sich atmen spüren. Atmen sie nun gleichmäßig ein und aus und achten darauf, wie sich ihre Bauchdecke beim Einatmen hebt und beim Ausatmen senkt.

Stellen Sie sich vor, ihr gesamter Bauch wäre eine Lunge. Füllen sie den Bauch mit Luft, weiten sie beim Einatmen die gesamte Bauchhöhle und spüren, wie die Luft ihre Muskulatur dehnt.

Beim Ausatmen pressen sie die Luft ein wenig und lassen sie zwischen den Lippen zischen. Das hört sich an, wie ein entlastendes »Pfff. « nach einer großen Anstrengung. Genießen Sie das Gefühl, das sich bald einstellen wird. Spüren Sie ihre Muskeln im Bauch, im Becken und im Brustkorb.

Die Übung sollte etwa zehn Minuten dauern. Danach strecken Sie sich, atmen tief ein und machen nach einer kleinen Pause mit den folgenden Übungen weiter. Wichtig: Sie müssen die Atemübung beherrschen, um weiter machen zu können. Ist Ihre Atmung verkrampft und nicht entspannt, haben die weiteren Übungen keinen Sinn. Warten Sie einfach ein wenig und versuchen es dann erneut. Will es trotz mehrfacher Versuche nicht klappen, sollten Sie einen entsprechenden Kurs mit fachkundiger Anleitung belegen.

Гњbungen, um den Beckenboden wahrzunehmen

Die Anspannung des Beckenbodens ertasten Männer am einfachsten an der Peniswurzel oder am Damm. Das ist der Bereich zwischen After und Hodensack. Nehmen Sie die gleiche Stellung ein, die Sie auch bei der Atemübung eingenommen haben. Dann ertasten Sie den Damm bzw. die Peniswurzel. Spannen Sie nun der Reihe nach Gesäßmuskulatur und Beinmuskulatur an. Ziehen Sie den After zusammen und drücken Sie ihre Harnröhre ab. Stellen Sie dich dazu vor, Sie wollten eine Blähung in sich halten oder den Urin anhalten.

Halten Sie die Spannung einige Sekunden, dann lassen Sie locker und konzentrieren sich auf die Muskulatur in ihrem Becken. Es geht darum, dass Sie ein GefГјhl bekommen, wann Sie Ihre Muskeln dort angespannt bzw. gelockert haben.

Üben Sie so lange, bis dass Sie wirklich ein Gefühl dafür haben, wann Ihre Beckenbodenmuskulatur angespannt ist. Sie können die Anspannung stets mit dem Erstasten des Dammes bzw. der Peniswurzel überprüfen.

WeiterfГјhrende Techniken

Die ersten Übungen werden alle in Rückenlage ausgeführt. Die Beine sind hochgelagert und Bauch samt Beckenboden sind entlastet. Später, wenn Sie spüren, wann Ihre Muskeln dort gespannt sind, können Sie flacher liegen oder eine ganz andere Haltung einnehmen. Im Prinzip können Sie liegen oder sitzen, das ist völlig egal.

Konzentrieren Sie sich zunehmend auf die Kraft, mit der Sie die Muskeln anspannen. Dies ist wichtiger, als die Dauer der Anspannung. Mit dem Fortschritt Ihrer Wahrnehmung beziehen Sie die Atmung mit in die Übungen ein. Spannen Sie beim Ausatmen an und lassen beim Einatmen locker. Nehmen Sie nach und nach andere Muskelgruppen mit hinzu. Ziehen Sie bei der Anspannung Ihren Bauch ein, das stärkt weitere wichtige Muskeln.

Versuchen Sie diese Übungen am Anfang täglich durchzuführen. Es geht, wie schon gesagt, fast überall.

Spezielle Гњbungen fГјr den betroffenen Mann

Stellen Sie sich vor, Ihre Eichel sei der Kopf einer Schildkröte. Ziehen Sie die Eichel immer wieder für einige Sekunden zurück in Ihren Bauchraum. Dann verringern Sie den Abstand zwischen After und Penis, um diesen dann zum Bauchnabel hochzuheben. Das stärkt die erwähnten Muskeln zur Erektionsfähigkeit enorm. Zusammen mit der Übung, den Harn anhalten zu wollen, sind das die besten Übungen, die man für ein erfolgreiches Training gegen Impotenz anraten kann.

Rating: 2.3/5 (18 votes cast)

Beckenbodentraining & Beckenbodengymnastik gegen Impotenz, vorzeitigen Samenerguss und Inkontinenz ohne Medikamente – Die beschriebenen Beckenbodengymnastik-Methoden sind Гњbungen, mit der die Beckenbodenmuskulatur des Mannes gestГ¤rkt werden soll. Dies soll gegen Impotenz, gegen Inkontinenz und gegen einen vorzeitigen Samenerguss helfen.

Beckenbodentraining / Beckenbodengymnastik – gegen Impotenz, Inkontinenz, vorzeitiger Samererguss
Als Beckenboden bezeichnet man den muskulösen Boden des Beckenbereiches. Der Beckenboden stützt die Bauch- und Beckenorgane und spielt eine wichtige Rolle bei der willkürlichen Bewegung der Schließmuskeln. Ein zu schlaffer Beckenboden kann Stuhl- oder Harninkontinenz zur Folge haben. Die Peniswurzel ist im Beckenboden verankert. Auch die so genannten Potenzmuskeln ziehen durch den Beckenboden. Ist der Beckenboden zu schlaff kann es zu Impotenz, Inkontinenz oder vorzeitigem Samenerguss kommen. Ein untrainierter und erschlaffter Beckenboden reizt häufig die Prostata. Die Folge ist nicht selten eine Entzündung, eine so genannte Prostatitis.

Beckenbodentraining / Beckenbodengymnastik gegen Impotenz und Inkontinenz für Männer
Die Methode besteht lediglich aus sechs simplen Bewegungen, die die Beckenbodenmuskeln gezielt kräftigen sollen. Dadurch soll eine bessere Durchblutung und somit auch eine bessere Versorgung des Beckenbodens mit Sauerstoff erreicht werden. Ein kräftiger Beckenboden ist förderlich für die Potenz und die Empfindsamkeit beim Geschlechtsverkehr. Durch die Stärkung der Potenzmuskeln kann der vorzeitige Samenerguss (Orgasmus) hinausgezögert werden. In einer Studie der Universitätsklinik Köln, bekamen 80% der Studienteilnehmer ihre Impotenz mithilfe von gezieltem Beckenbodentraining, wie es auch bei dieser Methode praktiziert wird, in den Griff.
Auch die Inkontinenz kann in vielen Fällen mit gezieltem Beckenbodentraining kontrolliert werden. Im Gegensatz zu Potenzmittel wie Viagra ist diese Methode nebenwirkungsfrei. Zudem können die Übungen jederzeit zuhause oder unterwegs durchgeführt werden.

Rating: +2 (from 4 votes)

Beckenbodentraining für Männer. 2.3 out of 5 based on 18 ratings

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What Is Anosmia?

Most of us take our sense of smell for granted. But have you ever thought about what it would be like to not be able to smell something? The complete loss of smell is called anosmia (an-OHZ-me-uh). Without your sense of smell. food tastes different, you can’t smell the scent of a flower, and you could find yourself in a dangerous situation, unknowingly. For example, without the ability to detect odors, you wouldn’t smell a gas leak, smoke from a fire, or sour milk.

Taste and smell disorders send hundreds of thousands of Americans to the doctor each year. Fortunately, for most people, anosmia is a temporary nuisance caused by a severely stuffy nose from a cold. Once the cold runs its course, a person’s sense of smell returns.

But for some people, including many elderly, the loss of a sense of smell may persist. In addition, anosmia can be a sign of a more serious medical condition. Any ongoing problems with smell should be checked out by a doctor.

The Basics of Smell

A person’s sense of smell is driven by certain processes. First, a molecule released from a substance (such as fragrance from a flower) must stimulate special nerve cells (called olfactory cells) found high up in the nose. These nerve cells then send information to the brain. where the specific smell is identified. Anything that interferes with these processes, such as nasal congestion, nasal blockage, or damage to the nerve cells themselves, can lead to loss of smell.

The ability to smell also affects our ability to taste. Without the sense of smell, our taste buds can only detect a few flavors, and this can affect your quality of life.

Anosmia Causes

Nasal congestion from a cold, allergy. sinus infection. or poor air quality is the most common cause of anosmia. Other anosmia causes include:

  • Nasal polyps — small noncancerous growths in the nose and sinuses that block the nasal passage.
  • Injury to the nose and smell nerves from surgery or head trauma .
  • Exposure to toxic chemicals, such as pesticides or solvents.
  • Certain medications. including antibiotics. antidepressants. anti-inflammatory medication, heart medications, and others.
  • Cocaine abuse.
  • Old age. Like vision and hearing, your sense of smell can become weaker as you age. In fact, one’s sense of smell is most keen between the ages of 30 and 60 and begins to decline after age 60.
  • Certain medical conditions, such as Alzheimer’s disease. Parkinson’s disease. multiple sclerosis. nutritional deficiencies, congenital conditions, and hormonal disturbances.
  • Radiation treatment of head and neck cancers.

Continued

Anosmia Symptoms

The obvious sign of anosmia is a loss of smell. Some people with anosmia notice a change in the way things smell. For example, familiar things begin to lack odor.

Anosmia Diagnosis

If you experience a loss of smell that you can’t attribute to a cold or allergy or which doesn’t get better after a week or two, tell your doctor. Your doctor can take a look inside your nose with a special instrument to see if a polyp or growth is impairing your ability to smell or if an infection is present.

Further testing by a doctor who specializes in nose and sinus problems — an ear, nose, and throat doctor (ENT, or an otolaryngologist) — may be needed to determine the cause of anosmia. A CT scan may be necessary so that the doctor can get a better look of the area.

Anosmia Treatments

If nasal congestion from a cold or allergy is the cause of anosmia, treatment is usually not needed, and the problem will get better on its own. Short-term use of over-the-counter decongestants may open up your nasal passages so that you can breathe easier. However, if the congestion gets worse or does not go away after a few days, see your doctor. You may have an infection and need antibiotics. or another medical condition may be to blame.

If a polyp or growth is present, surgery may be needed to remove the obstruction and regain your sense of smell.

If you suspect a medication is affecting your sense of smell, talk to your doctor and see if there are other treatment options available that won’t affect your ability to smell. However, never stop taking a medication without first talking with your doctor.

Sometimes a person will regain his or her sense of smell spontaneously. Unfortunately, anosmia is not always treatable, especially if age is the cause. But there are steps you can take to make living with the inability to smell more pleasant and safer. For example, put fire detectors and smoke alarms in your home and office and take extra care with leftovers. If you have any doubt about a food’s safety, don’t eat it.

If you smoke, quit. Smoking can dull your senses, including your sense of smell.

WebMD Medical Reference Reviewed by Neil Lava, MD on April 18, 2015

Sources

American Rhinologic Society: “Loss of Taste and Smell Stinks!”

Mayo Clinic: “The Loss of Smell (Anosmia).”

American Academy of Family Physicians: “Smell and Taste Disorders: A Primary Care Approach.”

National Institutes of Health: “Smell Disorders.”

В© 2015 WebMD, LLC. All rights reserved.

October 2, 2014

Health roundup: Viagra & blindness, losing sense of smell, bowel cancer breakthrough, new breast cancer drug cocktail, on-off switch for aging cells

A lot of men are going to be unhappy about this. Viagra ‘may cause blindness': Ingredient in the drug can permanently affect sight, doctors warn

One theory is that erectile dysfunction drugs may obstruct an enzyme which is important for transmitting light signals from the retina to the brain. It is already known that sildenafil. the active ingredient in the erectile dysfunction medication, can cause temporary vision problems in some healthy people.

Doctors have now warned it could also cause permanent damage to the eyes of people with retinitis pigmentosa. People with normal sight that carry the gene for the condition may also be at risk, experts warn.

Retinitis pigmentosa is a rare hereditary condition that causes the cells in the retina – the area of the back of the eye which detects light – to degenerate and die. This can lead to difficulty seeing in dim light, loss of peripheral vision, and sometimes blindness.
About one in 50 people are likely to be carriers of genes which lead to the degeneration of cells in the retina.

Previous studies have linked Viagra and other anti-impotence drugs to side effects such as deafness. American researchers also found that men who used Viagra increased their risk of developing skin cancer.

Losing the sense of smell predicts death within five years, according to new research…. the sense of smell is the canary in the coal mine of human health. A study published today in the open access journal PLOS ONE, shows that losing one’s sense of smell strongly predicts death within five years, suggesting that the nose knows when death is imminent, and that smell may serve as a bellwether for the overall state of the body, or as a marker for exposure to environmental toxins.

The study involved more than 3,000 participants, all of them between 57 and 85 years old, from the National Social Life, Health, and Aging Project (NSHAP), a longitudinal study of factors affecting the well-being of older people living in America.

In 2005-6, Jayant Pinto of the University of Chicago and his colleagues asked all the participants to perform a simple test that involved identifying five common odors (rose, leather, fish, orange, and peppermint). using the number of incorrectly identified odours as a score of the severity of smell loss.

Loss of the sense of smell predicted death more accurately than did a diagnosis of cancer, heart failure or lung disease, the only other common cause of predicting it more accurately being severe liver damage. But the researchers stress that it is unlikely to be a cause of death itself, arguing only that it is a harbinger for what is to come, and suggesting two possible reasons why this might be so.

Scientists make bowel cancer breakthrough that targets 80 PER CENT of tumours… using existing arthritis drugs

Dr Toby Phesse, of the Walter and Eliza Hall Institute of Medical Research in Melbourne, said early data showed medication currently used to treat psoriasis, arthritis and minor fibrosis could help in the fight against the country’s second deadliest form of cancer. He said the lab’s focus was directed in signaling pathways and finding how to locate the pathways that stop tumors from growing.

‘We identified a weak pathway that we found had a certain mutation in 80 per cent of tumous but there was a considerable risk since the pathway requires normal cells of the intestine. If the pathway is targeted directly you could be affecting normal cells of the intestine.We had to come up with a new method and target a parallel pathway.’

This is what brought scientists to the existing medicines, JAK inhibitors. The scientific breakthrough found ‘JAK inhibitors’ responded to 80 per cent of the colon tumors that possess the certain mutation.The treatment has caused excitement because the drug only targeted cancer cells, leaving normal cells unharmed, leaving no side effects.

Dr Phesse said this is an exciting breakthrough that will help thousands of people who have colon cancer or face risk of developing tumors. ‘The main point is that the inhibitors already exist and have been approved,’ he said.

A new breast cancer drug from Roche has shown ‘unprecedented’ benefits in extending lives in a clinical trial….Experts urged its widespread use for women with an aggressive form of the disease.

Patients with a type of breast cancer known as HER2 positive, which makes up about a quarter of all breast cancers, who were given Perjeta on top of older medicine Herceptin and chemotherapy lived 15.7 months longer than those on Herceptin and chemotherapy alone. That is the longest extension to survival ever seen for a drug studied in metastatic breast cancer and also an unusually good result for any type of metastatic cancer, where disease has spread to other parts of the body.

The switch controls the growth of telomeres, the timekeepers of cells…In a new study published September 19th in the journal Genes and Development, scientists at the Salk Institute have discovered that telomerase, even when present, can be turned off.

Understanding how this “off” switch can be manipulated–thereby slowing down the telomere shortening process–could lead to treatments for diseases of aging (for example, regenerating vital organs later in life). Posted by Jill Fallon at October 2, 2014 7:07 PM | Permalink

Aging Changes in the Senses

Reference from A.D.A.M.

Back to Top Information

When you age, the way your senses (taste, smell, touch, vision, and hearing) are able to give you information about the world changes. Your senses become less acute, and you may have trouble distinguishing details.

Sensory changes can have a tremendous impact on your lifestyle. You may have problems with communication, enjoyment of activities, and social interactions. Sensory changes can contribute to a sense of isolation.

All of the senses receive information of some type from the environment (light, sound vibrations, and so on). This is converted to a nerve impulse and carried to the brain, where it is interpreted into a meaningful sensation.

Everyone requires a certain minimum amount of stimulation before a sensation is perceived. This minimum level is called the threshold. Aging increases this threshold, so the amount of sensory input needed to be aware of the sensation becomes greater. Changes in the body part related to the sensation account for most of the other sensation changes.

Hearing and vision changes are the most dramatic, but all senses can be affected by aging. Fortunately, many of the aging changes in the senses can be compensated for with equipment such as glasses and hearing aids or by minor changes in lifestyle.

Back to Top Hearing

Your ears have two jobs. One is hearing and the other is maintaining balance. Hearing occurs after vibrations cross the eardrum to the inner ear. They are changed into nerve impulses and carried to the brain by the auditory nerve.

Balance (equilibrium) is controlled in a portion of the inner ear. Fluid and small hairs in the semicircular canal (labyrinth) stimulate the nerve that helps the brain maintain balance.

As you age, your ear structures deteriorate. The eardrum often thickens and the inner ear bones and other structures are affected. It often becomes increasingly difficult to maintain balance.

Hearing may decline slightly, especially that of high-frequency sounds, particularly in people who have been exposed to a lot of noise when younger. This age-related hearing loss is called presbycusis .

The sharpness (acuity) of hearing may decline slightly beginning about age 50, possibly caused by changes in the auditory nerve. In addition, the brain may have a slightly decreased ability to process or translate sounds into meaningful information. Impacted ear wax is another cause of trouble hearing and is more common with increasing age. Impacted ear wax may be removed in your doctor”s office.

Some hearing loss is almost inevitable. It is estimated that 30% of all people over 65 have significant hearing impairment.

Conductive hearing loss occurs when sound has problems getting through the external and middle ear. Surgery or a hearing aid may be helpful for this type of hearing loss, depending on the specific cause.

Sensorineural hearing loss involves damage to the inner ear, auditory nerve, or the brain. This type of hearing loss may or may not respond to treatment.

Persistent, abnormal ear noise (tinnitus ) is another fairly common hearing problem, especially for older adults.

Back to Top Vision

Vision occurs when light is processed by your eye and interpreted by your brain. Light passes through the transparent eye surface (cornea).

Your pupil is an opening to the eye interior. It becomes larger or smaller to regulate the amount of light that enters your eye. The colored portion ( iris ) is a muscle that controls the pupil size.

The inside of your eye is filled with a gel-like fluid. There is a flexible, transparent lens that focuses light on your retina (the back of the eye). Your retina converts light energy into a nerve impulse that is carried to the brain and interpreted.

Some age-related eye changes may begin as early as your 30s. Aging eyes produce less tears. Dry eyes can be quite uncomfortable. Many people find relief by using eyedrops or artificial tears solutions.

All of the eye structures change with aging. The cornea becomes less sensitive, so injuries may not be noticed. By the time you turn 60, your pupils decrease to about one-third of the size they were when you were 20.

The pupil may also react more slowly in response to darkness or bright light. The lens becomes yellowed, less flexible, and slightly cloudy. The fat pads supporting the eye decrease and the eye sinks back into the socket. The eye muscles become less able to fully rotate the eye.

As you age, the sharpness of your vision (visual acuity ) may gradually decline. Glasses or contact lenses may help correct age-related vision changes. You may eventually need bifocals.

Almost everyone older than 55 needs glasses at least part of the time. However, the amount of change is not universal. Only 15% to 20% of older people have bad enough vision to impair driving ability, and only 5% become unable to read. The most common problem is difficulty focusing the eyes (a condition called presbyopia ).

You may be less able to tolerate glare, and you may find that you have more trouble adapting to darkness or bright light. Many older people find that although their vision is good enough to drive during the day, they must give up night driving because of problems with glare, brightness, and darkness. Significant difficulty with night driving may be the first sign of a cataract (a clouding of the eye lens).

Indoor glare, such as glare from a shiny floor in a sunlit room, can also make it difficult to get around inside.

For people of all ages, it is harder to distinguish blues and greens than it is to distinguish reds and yellows. This becomes even more pronounced with aging. As your age increases, using warm contrasting colors (yellow, orange, and red) in your home can improve your ability to tell where things are and makes it easier to perform daily activities.

Many older people find that keeping a red light on in darkened rooms (such as the hallway or bathroom) makes it easier to see than using a “regular” night light. Red light produces less glare than a regular incandescent bulb.

With aging, the fluid inside your eye may change. Small particles can create “floaters” in your vision. Although annoying, floaters oftentimes do not indicate a dangerous condition and usually do not reduce vision. If you suddenly develop floaters or experience a rapid increase in the number of them, you should definitely have your eyes checked by a professional.

When your eyes are examined, you may not be able to move your eye in all directions. Your upward gaze may be limited. The area in which objects can be seen (visual field ) gets smaller.

Reduced peripheral vision is common and can limit social interaction and activity. Older people may not communicate with people sitting next to them because they cannot see them well — or perhaps at all. Food and drinks may be spilled. Driving can become dangerous.

Common eye disorders in the elderly (changes that are NOT normal) include cataracts, glaucoma. senile macular degeneration. and diabetic and hypertensive retinopathy .

Back to Top Taste and Smell

The senses of taste and smell interact closely, helping you appreciate food. Most taste really comes from odors. The sense of smell begins at nerve receptors high in the membranes of the nose.

You have approximately 9,000 taste buds. Your taste buds are primarily responsible for sensing sweet, salty, sour, and bitter tastes.

Smell (and to a lesser extent, taste) also play a role in both safety and enjoyment. We detect certain dangers, such as spoiled food, noxious gases, and smoke with taste and smell. A delicious meal or pleasant aroma can improve social interaction and enjoyment of life.

The number of taste buds decreases beginning at about age 40 to 50 in women and at 50 to 60 in men. Each remaining taste bud also begins to atrophy (lose mass). The sensitivity to the four taste sensations does not seem to decrease until after age 60, if at all. If taste sensation is lost, usually salty and sweet tastes are lost first, with bitter and sour tastes lasting slightly longer.

Additionally, your mouth produces less saliva as you age. This causes dry mouth, which can make swallowing more difficult. It also makes digestion slightly less efficient and can increase dental problems.

The sense of smell may diminish, especially after age 70. This may be related to loss of nerve endings in the nose.

Studies about the cause of decreased sense of taste and smell with aging have conflicting results. Some studies have indicated that normal aging by itself produces very little change in taste and smell. Rather, changes may be related to diseases, smoking, and environmental exposures over a lifetime.

Regardless of the cause, decreased taste and smell can lessen your interest and enjoyment in eating. Some people become less aware of personal hygiene when the sense of smell is decreased. Enjoyment of your environment may be diminished.

Sometimes changes in the way food is prepared, such as a change in the spices used, may help.

For some people, there is an increased risk of asphyxia because they cannot detect the odor of natural gas from the stove, furnace or other appliance. A visual gas detector that changes appearance when natural gas is present may be helpful.

Back to Top Touch, Vibration and Pain

The sense of touch also includes awareness of vibrations and pain. The skin, muscles, tendons, joints, and internal organs have receptors that detect touch, temperature, or pain.

Your brain interprets the type and amount of touch sensation. It also interprets the sensation as pleasant (such as being comfortably warm), unpleasant (such as being very hot) or neutral (such as being aware that you are touching something).

Medications, brain surgery. problems in the brain, confusion. and nerve damage from trauma or chronic diseases such as diabetes can change this interpretation without changing awareness of the sensation. For example, you may feel and recognize a painful sensation, but it does not bother you.

Some of the receptors give the brain information about the position and condition of internal organs. Even though you may not be consciously aware of this information, it helps to identify changes (for example, the pain of appendicitis ).

Many studies have shown that with aging, you may have reduced or changed sensations of pain, vibration, cold, heat, pressure, and touch. It is hard to tell whether these changes are related to aging itself or to the disorders that occur more often in the elderly.

It may be that some of the normal changes of aging are caused by decreased blood flow to the touch receptors or to the brain and spinal cord. Minor dietary deficiencies, such as decreased thiamine levels, may also be a cause of changes.

Regardless of the cause, many people experience changes in the touch-related sensations as they age. You may find it harder, for example, to tell the difference between cool and cold. Decreased temperature sensitivity increases the risk of injuries such as frostbite. hypothermia. and burns .

Reduced ability to detect vibration, touch, and pressure increases the risk of injuries, including pressure ulcers. After age 50, many people have reduced sensitivity to pain. You may develop problems with walking because of reduced ability to perceive where your body is in relation to the floor.

Fine touch may decrease. However, some people develop an increased sensitivity to light touch because of thinner skin (especially people older than 70).

To increase safety, make allowances for changes in touch-related sensations:

  • Limit the maximum water temperature in your house (there is an adjustment on the water heater) to reduce the risk of burns.
  • Look at the thermometer to decide how to dress rather than waiting until you feel overheated or chilled.
  • Inspect your skin (especially your feet) for injuries, and if you find an injury, treat it. Don”t assume that just because an area is not painful, the injury is not significant.

More Information on This Topic

Review Date: 1/18/2007
Reviewed By: Sandra W. Cohen, M.D. Private Practice specializing in geriatrics, Brooklyn, NY. Review provided by VeriMed Healthcare Network.

A.D.A.M. Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC’s accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.’s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).

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The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only — they do not constitute endorsements of those other sites. В© 1997- 2008 A.D.A.M. Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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Viagra ® (sildenafil citrate ) is licensed for the treatment of erectile dysfunction (also known as ED ). Most men tolerate the medication without any problems; however, there are some potential dangers with Viagra to be aware of. For example, it may cause serious side effects, such as vision problems or hearing loss, that often require prompt medical attention.

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To ensure a safe, effective treatment process, tell your healthcare provider about any other medication you are taking, including vitamins, supplements, and nonprescription products, and provide a complete medical history, detailing any other medical conditions you have.

(Click Viagra Side Effects and Viagra Precautions and Warnings for more information on potential dangers of Viagra. These articles provide a more complete list of side effects and go into more detail about who should avoid this drug and why.)

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Many men may be tempted to enhance their sexual performance with drugs for erectile dysfunction (ED) when they don’t really need them. But abusing these drugs can really damage your health and is not recommended.

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If you are looking to boost your sexual performance, learn how to increase testosterone naturally instead of relying on medications. A healthy lifestyle will go a long way toward helping you in the bedroom. Exercising, maintaining a healthy weight, managing stress and not smoking are going to help your sexual performance. There are also several supplements and foods that can help boost testosterone.

One supplement formulation contains ingredients that help support men’s sexual health and natural testosterone production: EveryDay Male® is a daily supplement that contains 13 ingredients that help men increase libido and ability to maintain erections. EveryDay Male® helps men dealing with other symptoms of low T such as improving mood, strength and lean muscle mass. Some of the ingredients include amino acids such as L-arginine for erectile health as well as acetyl-L-carnitine and L-citrulline.

Helpful Foods

Foods can also boost sexual performance. These include beets, pistachios, watermelon, oatmeal and pomegranate . These foods are safe and natural and do not put your health at risk or cause cardiovascular risks for you. In fact, these foods are good for your heart. Eating other heart-healthy foods, like the foods found in the Mediterranean diet, improves your cardiovascular health. That, in turn, improves the quality of your erections, which depend on good blood flow. In fact, ED can be a sign of heart disease ; both conditions can be caused by clogged arteries.

The bottom line is if you are looking to enhance your sexual performance, be informed and look toward natural ways to boost your testosterone and erectile strength. Supplements, foods and a heart-healthy lifestyle can give you every day sexual benefits; but taking ED drugs when you don’t need them makes you dependent on them to get an erection. If you take medications when you don’t have ED, you might be giving yourself ED because, as a consequence, you may not be able to get erections when you are not taking them.

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Wireless Innovation Alliance // Jun. 16

Earlier today, Reps. Darrell Issa (R-CA) and Anna Eshoo (D-CA) sent the attached letter to FCC Chairman Tom Wheeler on the importance of establishing the technical rules necessary to allow unlicensed use of the 600 MHz band. The Wireless Innovation Alliance (WIA) released the statement below in response. More

Wireless Innovation Alliance // Apr. 17

The Wireless Innovation Alliance (WIA) released the statement below on today’s FCC Open Meeting where the Commission approved an order to implement a spectrum sharing framework in the 3550-3700 MHz band. More

Wireless Internet Service Providers Association // 10:05 AM EST// Mar. 23

The National Association of Broadcasters (NAB) wants the FCC to declare an “emergency” and shut down the databases that let small businesses and others deliver broadband over vacant spectrum near television channels. More

Wireless Innovation Alliance // 6:06 PM EST// Feb. 10

The Wireless Innovation Alliance (WIA) released the statement below in response to the introduction of the House and Senate Wi-Fi Innovation Act More

Wireless Innovation Alliance // 4:44 PM EST// Jan. 28

The Wireless Innovation Alliance applauds the FCC for telling Marriott International, Inc. – and everyone else – that it is illegal to interfere with lawful communications. More

Wireless Innovation Alliance // 3:00 PM EST// Dec. 15

This October, the FCC found Marriott’s Gaylord Opryland Hotel and Convention Center to be guilty of blocking guests’ personal Wi-Fi hotspots and fined Marriott International $600,000. Lend your social voice to our Thunderclap. More

Wireless Innovation Alliance // 5:47 PM EST// Sep. 4

FCC Chairman Tom Wheeler acknowledged the critical role unlicensed spectrum plays in growing competition in the broadband marketplace stating that the FCC’s “efforts to expand the amount of unlicensed spectrum creates alternative competitive pathways.” More

The Hill // 9:25 AM EST// Jun. 16

CEA released a report, Unlicensed Spectrum and the American Economy, examining the economic impact of unlicensed spectrum on the American economy. More

The Wireless Innovation Alliance (WIA) is a broad-based group of innovators, providers, consumer groups, think tanks and education organizations that believe that more efficient use and expanded access to the nation’s spectrum resources are fundamental to the future of U.S. economic policy and global competitiveness, and that we face potential spectrum scarcities in both licensed and unlicensed bands that must be addressed in order for innovation and investment to move forward.

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GENERIC NAME(S): SILDENAFIL CITRATE

Uses

Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction -ED). In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a man get and keep an erection.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

Sildenafil is also available in other brands and strengths for treating high blood pressure in the lungs (pulmonary hypertension ). Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction -ED or pulmonary hypertension (such as tadalafil, vardenafil).

How to use Viagra

Read the Patient Information Leaflet provided by your pharmacist before you start taking sildenafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

To treat erectile dysfunction -ED, take this drug by mouth as directed by your doctor, usually as needed. Take sildenafil at least 30 minutes, but no more than 4 hours, before sexual activity (1 hour before is the most effective). Do not take more than once daily.

A high-fat meal may delay how quickly the drug begins to work.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Tell your doctor if your condition does not improve.

Side Effects

Dizziness. headache. flushing, or stomach upset may occur. Vision changes such as increased sensitivity to light, blurred vision. or trouble telling blue and green colors apart may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Sexual activity may put extra strain on your heart. especially if you have heart problems. If you have heart problems and experience any of these serious side effects while having sex. stop and get medical help right away: severe dizziness, fainting. chest/jaw/left arm pain, nausea .

Rarely, sudden decreased vision. including permanent blindness, in one or both eyes (NAION) may occur. If this serious problem occurs, stop taking sildenafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease. diabetes. high cholesterol. certain other eye problems (“crowded disk”), high blood pressure. if you are over 50, or if you smoke.

Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking sildenafil and get medical help right away if these effects occur.

In the rare event you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and get medical help right away, or permanent problems could occur.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction. including: rash. itching /swelling (especially of the face/tongue /throat), severe dizziness, trouble breathing .

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure), stroke in the past 6 months, kidney disease, liver disease, high or low blood pressure. a severe loss of body water (dehydration), penis conditions (such as angulation, fibrosis/scarring, Peyronie’s disease ), history of painful/prolonged erection (priapism), conditions that may increase the risk of priapism (such as sickle cell anemia. leukemia, multiple myeloma ), eye problems (such as retinitis pigmentosa. sudden decreased vision, NAION).

This drug may make you dizzy or cause vision problems. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This brand of the drug is usually not used in women. During pregnancy, sildenafil should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

A product that may interact with this drug is: riociguat.

Sildenafil can cause a serious drop in your blood pressure when used with nitrates. A serious drop in blood pressure can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use sildenafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide), recreational drugs called “poppers” containing amyl nitrate, amyl nitrite, or butyl nitrite.

If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of sildenafil to minimize your risk of low blood pressure.

Other medications can affect the removal of sildenafil from your body, which may affect how sildenafil works. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), HIV protease inhibitors (such as ritonavir, saquinavir), hepatitis C virus protease inhibitors (such as boceprevir, telaprevir), mifepristone, rifampin, among others.

Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as tadalafil, vardenafil).

Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include severe dizziness, fainting, painful/prolonged erection.

Notes

Do not share this medication with others.

Missed Dose

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised October 2015. Copyright(c) 2015 First Databank, Inc.

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Viagra

GENERIC NAME(S): SILDENAFIL CITRATE

Uses

Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction -ED). In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a man get and keep an erection.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

Sildenafil is also available in other brands and strengths for treating high blood pressure in the lungs (pulmonary hypertension ). Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction -ED or pulmonary hypertension (such as tadalafil, vardenafil).

How to use Viagra

Read the Patient Information Leaflet provided by your pharmacist before you start taking sildenafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

To treat erectile dysfunction -ED, take this drug by mouth as directed by your doctor, usually as needed. Take sildenafil at least 30 minutes, but no more than 4 hours, before sexual activity (1 hour before is the most effective). Do not take more than once daily.

A high-fat meal may delay how quickly the drug begins to work.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Tell your doctor if your condition does not improve.

Side Effects

Dizziness. headache. flushing, or stomach upset may occur. Vision changes such as increased sensitivity to light, blurred vision. or trouble telling blue and green colors apart may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Sexual activity may put extra strain on your heart. especially if you have heart problems. If you have heart problems and experience any of these serious side effects while having sex. stop and get medical help right away: severe dizziness, fainting. chest/jaw/left arm pain, nausea .

Rarely, sudden decreased vision. including permanent blindness, in one or both eyes (NAION) may occur. If this serious problem occurs, stop taking sildenafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease. diabetes. high cholesterol. certain other eye problems (“crowded disk”), high blood pressure. if you are over 50, or if you smoke.

Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking sildenafil and get medical help right away if these effects occur.

In the rare event you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and get medical help right away, or permanent problems could occur.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction. including: rash. itching /swelling (especially of the face/tongue /throat), severe dizziness, trouble breathing .

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure), stroke in the past 6 months, kidney disease, liver disease, high or low blood pressure. a severe loss of body water (dehydration), penis conditions (such as angulation, fibrosis/scarring, Peyronie’s disease ), history of painful/prolonged erection (priapism), conditions that may increase the risk of priapism (such as sickle cell anemia. leukemia, multiple myeloma ), eye problems (such as retinitis pigmentosa. sudden decreased vision, NAION).

This drug may make you dizzy or cause vision problems. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This brand of the drug is usually not used in women. During pregnancy, sildenafil should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

A product that may interact with this drug is: riociguat.

Sildenafil can cause a serious drop in your blood pressure when used with nitrates. A serious drop in blood pressure can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use sildenafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide), recreational drugs called “poppers” containing amyl nitrate, amyl nitrite, or butyl nitrite.

If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of sildenafil to minimize your risk of low blood pressure.

Other medications can affect the removal of sildenafil from your body, which may affect how sildenafil works. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), HIV protease inhibitors (such as ritonavir, saquinavir), hepatitis C virus protease inhibitors (such as boceprevir, telaprevir), mifepristone, rifampin, among others.

Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as tadalafil, vardenafil).

Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include severe dizziness, fainting, painful/prolonged erection.

Notes

Do not share this medication with others.

Missed Dose

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised October 2015. Copyright(c) 2015 First Databank, Inc.

Images

The Food and Drug Administration (FDA) says it agreed with the manufacturer, Pfizer, on extra wording on the drug’s label, after reports of deaths and severe side-effects among Viagra users.

While stressing that it still believes Viagra is safe, the FDA says the new warnings make clear that patients with a history of particular health problems should be carefully examined by a doctor before they are prescribed the drug.

Since Viagra went on the market in April, 69 men have been reported to have died after taking it.

“The revised labelling addresses post-marketing reports of heart attacks, sudden cardiac deaths and hypertension,” the FDA said in a statement.

History of heart problems or low blood pressure is seen as a risk factor

It said that many groups had been left out from the original safety trials for Viagra, including men who had suffered heart attacks, stroke or dangerous arrhythmia within six months, men with dangerously high or low blood pressure, men with heart failure or unstable angina (chest pains), or retinitis pigmentosa, an eye disorder.

“The new labelling notes that if Viagra is prescribed for these patients, it should be done with caution,” the FDA said.

It also noted that patients who have heart disease are at risk from sexual activity anyway and have to be especially careful if they use Viagra.

The new label also warns of the risk of priapism – a prolonged and painful erection – and advises patients to seek prompt medical attention if their erection lasts longer than four hours.

Plane crash connection investigated

Meanwhile, accident investigators in the United States say they are trying to determine whether Viagra contributed to a plane crash in which the pilot – a Hollywood actor, William Knight – was killed.

Mr Knight, 56, who has appeared in films such as Wall Street and Born on the Fourth of July, was killed when his experimental light aircraft hit the water during a difficult manoeuvre.

A police spokeswoman has confirmed that officials of the National Transportation Safety Board have asked a medical examiner to determine whether Mr Knight – an experienced pilot – was using Viagra.

The American aviation authorities have advised pilots against using the drug within six hours of flying, because its side-effects can include difficulty in distinguishing between blue and green, which are used extensively in airport lighting and cockpit instruments.

During testing, Pfizer reported that 3% of men reported visual disturbances that ranged from sensitivity to light to seeing a bluish-green haze.

Viagra and Vision

With an ex-Presidential candidate as its pitchman, more mentions on late-night talk shows than Joan Embry and the dubious honor of being the world’s top pharmaceutical treatment for impotence, few drugs in history have been more in the public eye more than Viagra – or gotten more attention for affecting the public’s eyes. Along with its impact below the belt, Viagra (sildenafil citrate) is well-documented to cause retinal dysfunction lasting several hours after it is taken. Most commonly, it causes increased light sensitivity, blurring, and a bluish tint or haze to vision in many men who take the medication. Since receiving FDA approval in March 1998, Viagra has been prescribed more than 22 million times in the U.S. alone and is available in 90 other countries, according to manufacturer Pfizer. Here’s what you need know about Viagra and your vision:

Who is most likely to get ocular side effects?
Viagra is available in three prescribed doses – 25, 50 and 100 mg pills. Side effects are usually dose-related, meaning the greater the dosage, the greater the risk. According to reports by Pfizer and subsequent studies, ocular side effects occur in:

  • About 3 percent of men taking doses of 25-50 mg
  • About 11 percent taking 100 mg doses
  • About 50 percent of men taking 200 mg
  • Nearly all men taking 600 to 800 mg.

Why does Viagra cause vision changes? Viagra is effective on erectile dysfunction because it inhibits phosphodiesterase 5 (PDE-5), an enzyme that enhances the effects of nitric oxide, which is released during sexual stimulation to relax the smooth muscle of the penis and facilitate blood inflow. However, the drug also has a milder inhibiting effect on PDE-6, an enzyme actively present in retinal photoreceptors. This causes an increase in the concentration of cyclicGMP, resulting in a depolarization of the rod cell – and increased light sensitivity and the infamous “blue vision.”

When do side effects occur? The side effects are short-lived and generally peak within 1-2 hours after the drug is taken. What is the long-term vision damage? Hard to say, since the drug has been on the market for only a few years. So far, no long-term retinal damage has been reported, but then again, long-term electroretinograms (ERG) have not been done, says Michael F. Marmor, MD, a Stanford retinal specialist who has published studies on the ophthalmic effects of Viagra. He believes the drug could conceivably result in lasting damage to photoreceptors, so he recommends that you avoid it if you have macular degeneration, diabetic retinopathy, retinitis pigmentosa or other retinal disease. (Meanwhile, Viagra’s own label issues warnings to patients with existing AMD or retinitis pigmentosa because they were not studied in past clinical trials.)

Posted: Oct. 29, 2001

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Viagra Super Active

Herbal ED Treatment

Herbal treatment for impotence includes several herbs and herbal supplements. If a man prefers the natural way of treatment, the herbal supplements are not the option. The supplements are not recommended by FDA in the cure for the sexual disease. Besides, FDA warns that very often these products do not contain the real information about the chemicals that comprise the composition of these herbals. Usually, the manufacturers of these botanicals do not mention the chemicals on the package that can influence the health of a man and even interact with certain drugs and food products. The herbal supplements are not FDA approved, so their efficiency in the cure for impotence is doubtful. The same is about the penile creams that have not been tested according to the demands of the organization.

However, impotence can be treated by the herbs and certain elements found in the food products. The intake of the natural plants and their roots can work wonders for impotent men. In some cases, such treatment can prevent ED and even stimulate an erection, if this method is regularly used. The first effective amino acid is called L-arginine. This acid can be found in such products as poultry, fish, red meat and dairy products. The scientists have studied this method for ED cure and they approved its safety and possible positive influence on the erectile function. As it is a vasodilator, L-arginine widens the blood vessels – the principle of work that reminds the PDE 5 inhibitors in the formula of ED drugs.

Another safe ED cure is the intake of dehydroepiandrosterone. A male body produces this hormone. However, one can take it from the combination of soy and wild yam. The studies of this method have shown that it is safe for the male health and it can be effective in ED cure if this sexual disease is not caused by diabetes and certain nerve disorders. Unfortunately, this method can cause hair loss and upset of stomach. Some drug may interact with this hormone in a negative way. The treatment therapy should last several months to have some effect. The most effective herbal treatment is the intake of the red ginseng.

Viagra Super Active

The pharmaceutical company Dr. Johns created the gel form of Viagra tablets. A gel capsule form dissolves faster than the simple tablet. Besides, it can stay in the blood flow up to 6 hours. Sildenafil gel capsules provide better and faster dissolution of the PDE 5 inhibitor. This medicine needs to be prescribed by a medical specialist qualified in the field of ED treatment. You may have to test your blood, hormones, the state of the sexual function and certain health conditions to be sure that this medicine is safe for the intake. Viagra Super Active is used to cure the symptoms of ED and its severe stage. You can buy Intagra online. This medicine includes the same PDE 5 inhbitor.

How to Take Viagra Gel Capsules?

With this ED medicine, the intake of the water glass is optional. The gel capsules with Viagra should be used in 15-20 minutes before intimacy. This medicine is capable of enhancing the erectile stimulation for 6 hours. Ask your urologist to prescribe the dosage. Read carefully the information on the prescription label. The dose of Viagra Super Active per one day is 100 mg of Sildenafil. The dosage may be decreased. But, it is not allowed to increase the daily dose of Sildenafil.

What to Avoid with Sildenafil Gel Capsules?

If you regularly take such drugs as nitrates, fungal pills, HIV medicines, blood tablets, other ED medicines with Sildenafil and grapefruit juice, avoid the intake of Viagra Super Active capsules. Some vitamins and herbal supplements can also influence the effect of this medicine. The intake of a fatty meal and the alcoholic drinks is also not allowed. Another ED drug produced in a gel capsule is Cialis Super Active 20 mg manufactured by Dr. Johns.

Contraindicated Diseases

Viagra Super Active is the ED medicine that should not be used by men with the following health conditions: liver failure, stroke, cardiac diseases, priapism, sickle cell anemia, leukemia, high blood pressure, penis deformations, hypersensitive reaction to Sildenafil and peyronie’s disease. Try Caverta pills if you prefer the simple ED tablets.

Viagra Super Active Side Effects

This drug can lead to dizziness, diarrhea, a mild headache, blurred vision, seizures, muscle pain, redness of the face, swelling and dyspepsia.

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Wireless Innovation Alliance // Jun. 16

Earlier today, Reps. Darrell Issa (R-CA) and Anna Eshoo (D-CA) sent the attached letter to FCC Chairman Tom Wheeler on the importance of establishing the technical rules necessary to allow unlicensed use of the 600 MHz band. The Wireless Innovation Alliance (WIA) released the statement below in response. More

Wireless Innovation Alliance // Apr. 17

The Wireless Innovation Alliance (WIA) released the statement below on today’s FCC Open Meeting where the Commission approved an order to implement a spectrum sharing framework in the 3550-3700 MHz band. More

Wireless Internet Service Providers Association // 10:05 AM EST// Mar. 23

The National Association of Broadcasters (NAB) wants the FCC to declare an “emergency” and shut down the databases that let small businesses and others deliver broadband over vacant spectrum near television channels. More

Wireless Innovation Alliance // 6:06 PM EST// Feb. 10

The Wireless Innovation Alliance (WIA) released the statement below in response to the introduction of the House and Senate Wi-Fi Innovation Act More

Wireless Innovation Alliance // 4:44 PM EST// Jan. 28

The Wireless Innovation Alliance applauds the FCC for telling Marriott International, Inc. – and everyone else – that it is illegal to interfere with lawful communications. More

Wireless Innovation Alliance // 3:00 PM EST// Dec. 15

This October, the FCC found Marriott’s Gaylord Opryland Hotel and Convention Center to be guilty of blocking guests’ personal Wi-Fi hotspots and fined Marriott International $600,000. Lend your social voice to our Thunderclap. More

Wireless Innovation Alliance // 5:47 PM EST// Sep. 4

FCC Chairman Tom Wheeler acknowledged the critical role unlicensed spectrum plays in growing competition in the broadband marketplace stating that the FCC’s “efforts to expand the amount of unlicensed spectrum creates alternative competitive pathways.” More

The Hill // 9:25 AM EST// Jun. 16

CEA released a report, Unlicensed Spectrum and the American Economy, examining the economic impact of unlicensed spectrum on the American economy. More

The Wireless Innovation Alliance (WIA) is a broad-based group of innovators, providers, consumer groups, think tanks and education organizations that believe that more efficient use and expanded access to the nation’s spectrum resources are fundamental to the future of U.S. economic policy and global competitiveness, and that we face potential spectrum scarcities in both licensed and unlicensed bands that must be addressed in order for innovation and investment to move forward.

Spectrum, and specifically, the most efficient and expansive use of this most valuable natural resource, is fundamental to the future of U.S. economic growth, and global competitiveness. United States spectrum policy must also be efficient and flexible as well, so that we can encourage and accommodate new and innovative ways to meet the growing demand for wireless services and applications, and the growing inability – in both licensed and unlicensed bands – to meet that demand.

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